Sildenafil-based options
A PDE5 inhibitor that helps increase blood flow to the penis during sexual stimulation. Typically used as needed.
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Four ingredients.
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Four ingredients.
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Treatment and formulation
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- Sildenafil (the active ingredient in Viagra®)
- Tadalafil (the active ingredient in Cialis®)
- Apomorphine (activates dopamine receptors involved in sexual response)
- Oxytocin (a hormone associated with bonding and intimacy)
No obligation · Prescription not guaranteed
See how it works ↓Prescription treatment is available only when a licensed provider determines it is medically appropriate. Featured imagery is illustrative; medication, formulation, and fulfillment depend on the prescribed plan. Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness, or manufacturing quality.
01Provider reviewedA licensed clinician makes every prescription decision.
02Private by designComplete your health check-in online from home.
03Clear before checkoutReview the prescribed plan and price before proceeding.
04Discreet fulfillmentOrders ship discreetly when treatment is prescribed.
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Choose what you need help with
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Complete your medical profile
Share medications, conditions, allergies, and risk factors.
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A licensed provider evaluates whether treatment is appropriate.
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Review your next step
If approved, see the plan and price before deciding to proceed.
Personalized options
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Tadalafil-based options
A longer-acting PDE5 inhibitor that helps increase blood flow to the penis during sexual stimulation. It may be prescribed as needed or once daily.
Apomorphine
A dopamine agonist that activates dopamine receptors involved in sexual response. Its FDA-approved use is for Parkinson’s “off” episodes—not ED.
Oxytocin
A naturally occurring peptide hormone associated with bonding and intimacy. FDA-approved oxytocin is not indicated for libido or ED.
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The clinical picture
Four ingredients.
One provider-guided plan.
Sildenafil and tadalafil are established PDE5 inhibitors for ED. Apomorphine is a dopamine agonist, and oxytocin is a peptide hormone.
Sildenafil
A shorter-window, as-needed oral treatment option.
Tadalafil
A longer-window option that may be prescribed as needed or daily.
Apomorphine
A dopamine agonist.
Oxytocin
A peptide hormone.
~1 HOURUsual sildenafil planning time 30 MIN+Tadalafil as-needed label timing UP TO 36HTadalafil activity window 1:1 REVIEWLicensed-provider decision
Illustrative imagery only. Timing references are based on FDA-approved oral tablet labeling; individual response varies and your prescribed instructions may differ.
Know your options
Four ingredients.
Different clinical roles.
Sildenafil and tadalafil have FDA-approved oral ED labeling. Apomorphine and oxytocin do not have FDA-approved labeling for ED or libido.
Established ED ingredientAdditional ingredient
Swipe to compare →
| Treatment path | Active ingredient | Use pattern | Label timing | Food |
|---|---|---|---|---|
| Shorter window | Sildenafil PDE5 inhibitor | As needed | Usually about 1 hour before; label permits 30 minutes to 4 hours before | With or without food |
| Longer window | Tadalafil PDE5 inhibitor | As needed or once daily, if prescribed | As-needed dosing may be taken at least 30 minutes before | Without regard to food |
| Additional ingredient | ApomorphineDopamine agonist | As prescribed | No FDA-approved ED labeling | Varies by prescribed formulation |
| Additional ingredient | OxytocinPeptide hormone | As prescribed | No FDA-approved libido labeling | Varies by prescribed formulation |
At-a-glance timing
Plan for tonight—or leave room for tomorrow.
These bars compare the activity windows reported in oral tablet labeling. They are not a promise of response time or duration.
0 12h 24h 36h
Sildenafil effect shown up to 4h
up to 4h
Tadalafil as-needed treatment window
up to 36h
● Sexual stimulation is still required. Individual response varies.
Never take sildenafil or tadalafil with nitrates or guanylate cyclase stimulators. Apomorphine and oxytocin are not FDA-approved for ED or libido treatment. This comparison is educational and is not a treatment recommendation.
Viagra® is a registered trademark of Pfizer Inc. Cialis® is a registered trademark of Eli Lilly and Company. HARDMD and DietsMD are not affiliated with either company.
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Review your prescribed treatment, price, and fulfillment details before moving forward. Approved orders are prepared and shipped discreetly by the dispensing pharmacy.
START MY PRIVATE CHECK-IN →Compare your options
Comparing online ED care?
If you’re considering BlueChew, Hims, Ro (Roman), Rex MD, Friday Plans, Rugiet, or another online ED service, compare the details that shape your care—not just the brand name.
Understand how your health history is evaluated and whether follow-up with a licensed provider is available.
Compare the medication, dose, dosage form, and instructions actually prescribed—not a headline ingredient list.
Check the full recurring cost, quantity, refill schedule, shipping charges, and whether membership fees apply.
Confirm who dispenses and ships a prescription, expected timing, and what happens if a delivery is delayed.
Eligibility, treatments, and service availability can vary by state and by an individual provider’s medical judgment.
Review cancellation, renewal, refill, and support policies before you decide which service fits your needs.
About HARDMD
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HARDMD is DietsMD’s provider-guided online ED care experience. It is a separate service and is not affiliated with or endorsed by BlueChew, Hims, Ro/Roman, Rex MD, Friday Plans, Rugiet, or their owners. Competitor offerings may change; verify current details directly with each provider.
Important safety information
What you should know before treatment.
Sildenafil and tadalafil are prescription medicines and are not right for everyone. Do not use PDE5 inhibitors with nitrates or guanylate cyclase stimulators because the combination can cause a dangerous drop in blood pressure. Tell your provider about every medical condition, medication, vitamin, and supplement you take.
Seek urgent medical care for an erection lasting more than four hours, sudden vision or hearing changes, chest pain, or other severe symptoms. Individual results vary. Treatment and results are not guaranteed.
Apomorphine is a dopamine agonist, but its FDA-approved labeling is for Parkinson’s disease—not ED. Oxytocin’s FDA-approved labeling does not establish a libido indication.
Read DietsMD policies ↗FAQs
Straight answers before you start.
Do I need to choose a medication first?+
No. Your health information and goals help a licensed provider decide which options, if any, may be medically appropriate.
Does the check-in guarantee a prescription?+
No. A provider may prescribe treatment, request more information, recommend another approach, or determine that prescription care is not appropriate.
When will I see pricing?+
If you are approved, you can review the applicable treatment, price, and fulfillment details before deciding whether to proceed.
Does HARDMD already include all four ingredients?+
Available ingredients, dose, and form depend on the prescribed plan and provider judgment.
Is HARDMD a BlueChew alternative?+
HARDMD is one option for adults exploring provider-guided online ED care. It is separate from and not affiliated with BlueChew. The right service depends on eligibility, available treatment, price, support, and a licensed provider’s medical judgment.
How does HARDMD compare with Hims or Ro (Roman)?+
Compare each service’s provider-review process, available treatments and dosage forms, total recurring price, refill and cancellation terms, pharmacy fulfillment, state availability, and support. Offerings can change, so verify current details directly with each service.
What should I compare across online ED services?+
Look beyond the brand name. Compare the actual medication and dose prescribed, provider access, total cost, quantity, refill schedule, dispensing pharmacy, shipping, state availability, support, and cancellation terms.
Will HARDMD provide the same medication as another ED service?+
Not necessarily. Available treatment, dose, and dosage form depend on your health profile, service availability, and the independent medical judgment of a licensed provider. A prescription is not guaranteed.
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